解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Five new 8-9' linked neolignans conchigeranals A-E (1-5), together with three known compounds galanganal (6), galanganols A (7) and B (8), were isolated from the whole plant of Alpinia conchigera. Their structures were established by spectroscopic analysis, including 2D-NMR spectroscopic techniques. Cytotoxicities of ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.08.011
更新日期:2013-12-01 00:00:00
abstract::The purpose of this investigation was to study the modulator and efflux pump inhibitor activity of coumarins isolated from Mesua ferrea against clinical strains as well as NorA-over expressed strain of Staphylococcus aureus 1199B. Seven coumarins were tested for modulator activity using ethidium bromide (EtBr) as a su...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.07.015
更新日期:2013-10-01 00:00:00
abstract::Diterpene alkaloids neoline (1), napelline (2), isotalatizidine (3), karakoline (4), senbusine A (5), senbusine C (6), aconitine (7) and taurenine (8) were identified from Aconitum napellus L. subsp. firmum, four (2-4, 6) of which are reported for the first time from this plant. The structures were determined by means...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.07.010
更新日期:2013-10-01 00:00:00
abstract::A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed to identify and quantify the camptothecin quaternary derivative CPT8 for application in pharmacokinetics and tissue distribution studies. Rat plasma and tissue samples were extracted with methanol by using camptothecin as the internal sta...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.06.012
更新日期:2013-10-01 00:00:00
abstract::A new degraded limonoid, named isodictamdiol A (1), two known degraded limonoids (2, 3) and a new nature product of quinoline alkaloid (4) along with five known quinoline alkaloids (5-9) were isolated from the root bark of Dictamnus angustifolius G. Don ex Sweet.. Certain useful NMR data were generalized to determine ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.07.023
更新日期:2013-10-01 00:00:00
abstract::A fast and efficient method for the isolation of the C-glucosidated xanthones mangiferin and isomangiferin from the South-African plant Cyclopia genistoides was developed for the first time. The procedure involved extraction, liquid-liquid partitioning with ethyl acetate and subsequent precipitation of mangiferin and ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.07.020
更新日期:2013-10-01 00:00:00
abstract::Glabridin, a prenylated isoflavonoid of G. glabra L. roots (European licorice, Fabaceae), has been associated with a wide range of biological properties such as antioxidant, anti-inflammatory, anti-atherogenic, regulation of energy metabolism, estrogenic, neuroprotective, anti-osteoporotic, and skin-whitening. While g...
journal_title:Fitoterapia
pub_type: 杂志文章,评审
doi:10.1016/j.fitote.2013.07.003
更新日期:2013-10-01 00:00:00
abstract::Four new compounds, including three new steroids (1-3) and one new sesquiterpene (6), and two new natural products (4-5), as well as three known steroids (7-9) were isolated from the twigs of Turraea pubescens. Compounds 3-5 are C₂₂ steroids isolated from the Meliaceae family for the first time. Their structures were ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.07.006
更新日期:2013-10-01 00:00:00
abstract::Two new glycosides, 2-methyl-L-erythritol-4-O-(6-O-trans-sinapoyl)-β-D-glucopyranoside (1) and 2-methyl-L-erythritol-1-O-(6-O-trans-sinapoyl)-β-D-glucopyranoside (2), along with two known triterpenoids (3-4), four quinic acid derivatives (5-8) and one flavonoid (9) were isolated from the fruit of Gardenia jasminoides....
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.05.018
更新日期:2013-09-01 00:00:00
abstract::Four new triterpenoids, sweriyunnangenin A (1), sweriyunnanosides A (2), B (3) and C (4), along with nineteen known compounds (5-23) were isolated from Swertia yunnanensis. Based on extensive spectroscopic analyses (1D- and 2D-NMR, HRESIMS, UV, IR, [α]D), the structures of sweriyunnangenin A (1), sweriyunnanosides A (...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.05.023
更新日期:2013-09-01 00:00:00
abstract::Two new alkaloids, named stenine A (1) and stenine B (2), along with the known compounds neostenine (3), stenine (4) and neotuberostemonine (5), were isolated from the roots of Stemona sessilifolia. Their structures were elucidated by 1D- and 2D-NMR spectra and X-ray single-crystal diffraction experiment. Anti-acetylc...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.06.010
更新日期:2013-09-01 00:00:00
abstract::Fourteen pregnane-type steroidal alkaloids were isolated from the ethanolic extracts of whole Sarcococca hookeriana var. digyna plants. Their structures were elucidated on the basis of spectral data. Three of them were identified as new steroidal alkaloids: (S)-20-(N,N-dimethylamino)-16α,17α-epoxy-3β-methoxy-pregn-5-e...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.04.010
更新日期:2013-09-01 00:00:00
abstract::Three new secoiridoids, swermacrolactones A-C (1-3), together with fourteen known compounds were isolated from Swertia macrosperma. Their structures were elucidated based on extensive spectroscopic analyses (IR, UV, MS, 1D and 2D NMR). By anti-HBV assay on the Hep G 2.2.15 cell line in vitro, the most active compound,...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.06.002
更新日期:2013-09-01 00:00:00
abstract::Goniothalamus macrophyllus (Blume) Hook. f. & Thoms. is a plant widely distributed in Malaysia. The aim of this study is to identify compounds from the roots of G. macrophyllus. The ground roots were extracted with aqueous methanol and partitioned sequentially with n-hexane, chloroform and butanol. Purification from t...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.03.028
更新日期:2013-07-01 00:00:00
abstract::One alkyl glycoside, saussurostelloside A (1), two phenolic glycosides, saussurostellosides B1 (2) and B2 (3), and 27 known compounds, including eleven flavonoids, seven phenolics, six lignans, one neolignan, one phenethyl glucoside and one fatty acid, were isolated from an ethanol extract of Saussurea stella (Asterac...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.03.027
更新日期:2013-07-01 00:00:00
abstract::The objective of this study was to evaluate potential hepatoprotective capabilities of quercetin in relation to its modulation of the HO-1 and NOS-2 activities in an experimental model of fulminant liver failure. Liver insult was induced by in vivo administration of D-galactosamine (d-GalN, 400 mg/kg, i.p.) and lipopo...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.03.016
更新日期:2013-06-01 00:00:00
abstract::The effect of asiaticoside isolated from Hydrocotyle sibthorpioides (AHS) on the promotion of cognition in senescence-accelerated mice (SAMP) was evaluated. Six-month old male SAMP8 mice were orally administered 20, 40 or 80 mg/kg AHS daily for three months. SAMR1 mice were used as a "normal aging" control. The result...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.03.023
更新日期:2013-06-01 00:00:00
abstract::Dragon's blood is a rare and precious traditional medicine used by different cultures since ancient times. However, studies on enhancing the rapid accumulation of dragon's blood in Dracaena cambodiana and determining its formation mechanism are unavailable. In this study, the activities of two fungi, namely, BJDC01 an...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.03.012
更新日期:2013-06-01 00:00:00
abstract::Before the design of brucine-containing transdermal formulations, the pharmacodynamics and pharmacokinetics of brucine following transdermal administration should be evaluated. In this study, the effect of addition of ethanol on solubility of bruicne was investigated and 20% ethanol was added into PBS to obtain 10mg/m...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2013.03.007
更新日期:2013-04-01 00:00:00
abstract::Different lines of experimental evidence indicate that treatment with extracts from and derivatives of Phaseolus vulgaris reduces intake of food, including highly palatable foods and beverages, in rats. The present study was designed to extend to mice these lines of evidence. To this end, CD1 mice were treated acutely...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.12.015
更新日期:2013-03-01 00:00:00
abstract::Three new mixed terpenoids, tricycloalternarenes (TCAs) F-H (1-3), together with ten known tricycloalternarenes (4-13), were isolated from the Czapek's culture of an endophytic fungus Ulocladium sp. Their structures were identified by extensive spectroscopic experiments (NMR and MS) and comparison with literature data...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.12.029
更新日期:2013-03-01 00:00:00
abstract::Hydroxysafflor yellow A (HSYA) is an active ingredient obtained from the flower of Carthamus tinctorius L. The present study investigated the effects of HSYA on lipopolysaccharide (LPS)-induced inflammatory signal transduction in human alveolar epithelial A549 cells. A549 cells stimulated with LPS were incubated with ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.11.004
更新日期:2013-01-01 00:00:00
abstract::The tea seed triterpene saponin (TS) from Camellia sinensis was found to exhibit better antitumor activity in vivo in S180 implanted ICR mice and QR inducing activity for hepa lclc7 cells respectively compared with the total tea seed saponin (TTS), hydrolysate of the TTS and tea seed flavonoid glycosides (TF). By bioa...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.12.022
更新日期:2013-01-01 00:00:00
abstract::Flos Chrysanthemi (the flower of Chrysanthemum morifolium Ramat.) is widely used in China as a food and traditional Chinese medicine for many diseases. Luteolin and apigenin are two main bioactive components in Flos Chrysanthemi, and chrysoeriol and diosmetin are two methylated metabolites of luteolin in vivo by cathe...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.09.011
更新日期:2012-12-01 00:00:00
abstract::This manuscript reports on the first CE-method suitable for analyzing twelve pharmacologically relevant compounds (flavonoids, caffeic acids and leontopodic acid) in the aerial parts of Leontopodium alpinum. By using a 60mM borax buffer containing 25mM SDS and 35% acetonitrile the analytes could be well resolved in 25...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.09.023
更新日期:2012-12-01 00:00:00
abstract::We investigated the effect of caffeoylserotonin (CaS) on THP-1 monocyte migration and adhesion to fibronectin in response to MCP-1. CaS decreased monocyte adhesion and migration induced by MCP-1, together with CCR2 expression and α5β1 integrin, and activated β1 integrin expression on the cell surface. CaS also inhibit...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.04.025
更新日期:2012-12-01 00:00:00
abstract::Oil production from the seeds of Camellia oleifera Abel. causes a great waste of shells which contain a lot of bioactive components. The aim of this research was to isolate flavonoid from the shells of C. oleifera Abel. and evaluate its uses. The shells were extracted by 70% methanol, hydrolyzed by 2M hydrochloric aci...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.09.006
更新日期:2012-12-01 00:00:00
abstract::A new lathyrane diterpene (1), an unreported spectroscopic data lathyrane diterpenene (2), and two known analaogues (3 and 4) have been isolated from Euphorbia prolifera. Their structures were elucidated as (12E,2S,3S,4R,5R,6S,9S,11S,15R)-3-butyryloxy-5,15-diacetoxy-6,17-epoxylathyra- 12-en-14-one (1), (12E,2S,3S,4R,5...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.06.014
更新日期:2012-10-01 00:00:00
abstract::Two new isocoumarins (1 and 2), a new alkaloid (3), and a known N-acetyldopamine dimer (4) were isolated from the ethyl acetate extract of Chinese insect medicine Eupolyphaga sinensis. Their structures were elucidated on the basis of detailed spectroscopic investigations, such as 1D- and 2D NMR spectroscopy, as well a...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.06.005
更新日期:2012-10-01 00:00:00
abstract::Salvianolic acid B (Sal B) is the most abundant phenolic compound in Salvia miltiorrhiza, which has been widely used for the treatment of cardiovascular diseases in Oriental medicine. To elucidate structure of the converted compounds of Sal B by decoction in aqueous solution, Sal B (200 mg) was decocted in an aqueous ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.06.015
更新日期:2012-10-01 00:00:00
abstract::A stimulatory effect of apigenin-6-C-β-fucopyranoside (1) on glucose uptake was observed when rat soleus muscle was incubated with 1, 10 and 100 μM of this flavonoid glycoside. The presence of specific insulin signaling inhibitors, such as wortmannin, an inhibitor of phosphoinositide 3-kinase (PI3K), RO318220, an inhi...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.07.003
更新日期:2012-10-01 00:00:00
abstract::Panax ginseng is an indigenous medicinal herb and has traditionally been used among Asian population for relief of many human ailments. We investigated the prophylactic role of Korean P. ginseng extract (KG) against X-ray irradiation-induced emesis in an acute rat pica model. Rats were treated with KG (12.5, 25, 50 mg...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.04.008
更新日期:2012-09-01 00:00:00
abstract::Psychotria is a complex genus whose neotropical species are known by the presence of glucosidic monoterpene indole alkaloids. These compounds are able to display a large range of effects on the central nervous system, such as anxiolytic, antidepressant, analgesic, and impairment of learning and memory acquisition. The...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.04.013
更新日期:2012-09-01 00:00:00
abstract::More attention was paid to the anti-tumor activity of Rhizoma Paridis (RP) recently, of which the wild resource was decreased significantly. This study was aimed to elucidate the chemical characteristics of Paris fargesii var. brevipetala (PFB) that may be administrated as alternate resource of legal RP. A HPLC-ELSD m...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.01.003
更新日期:2012-06-01 00:00:00
abstract::Two new pentacyclic triterpenes named kirmanoic acid (1) and kurramanoic acid (2) have been isolated from the chloroform-soluble portion of the whole plant of Nepeta clarkei Hook. The structures of the two new compounds were assigned on the basis of their ¹H and ¹³C NMR spectra including two-dimensional NMR techniques...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.01.002
更新日期:2012-04-01 00:00:00
abstract::The present study was designed to verify whether frutalin (FTL) affords gastroprotection against the ethanol-induced gastric damage and to examine the underlying mechanism(s). Gastric damage was induced by intragastric administration of 0.2 ml of ethanol (96%). Mice in groups were pretreated with FTL (0.25, 0.5 and 1 ...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2012.01.005
更新日期:2012-04-01 00:00:00
abstract::Since the extract from berries of Aronia melanocarpa presents antioxidative properties in plasma and in blood platelets, not only from healthy group, but also from patients with benign breast diseases and in patients with invasive breast cancer before surgery, the aim of our present study was to evaluate the oxidative...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2011.11.007
更新日期:2012-03-01 00:00:00
abstract::Isothiocyanates (ITCs), the breakdown products of glucosinolates found primarily in species of Brassicaceae (Cruciferae), are potential anti-cancer compounds. This review compiles data on how through different modes of action ITCs and their synthetic counterparts target leukemia. ...
journal_title:Fitoterapia
pub_type: 杂志文章,评审
doi:10.1016/j.fitote.2011.11.012
更新日期:2012-03-01 00:00:00
abstract::Bergenin, a major constituent of Caesalpinia digyna Rottler (Leguminosae) was isolated from its roots and was characterized by comparing its melting point and spectroscopic data (IR, (1)H, (13)C, Mass Spectra) with standard bergenin. Isolated bergenin was then evaluated for antidiabetic (Type 2) activity in streptozot...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2011.12.008
更新日期:2012-03-01 00:00:00
abstract::As part of our search for biologically active anti-osteoporotic agents that enhance the differentiation and mineralization of osteoblastic MC3T3-E1 cells, we identified the ginsenoside Rd as the most active compound among ginsenosides. In this study, we showed that Rd stimulates osteoblastic differentiation and minera...
journal_title:Fitoterapia
pub_type: 杂志文章
doi:10.1016/j.fitote.2011.10.017
更新日期:2012-01-01 00:00:00